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  5. Life Science

Office & Commercial

Life Science

Life Science illustration

Life science real estate development in the United States is a rapidly growing segment, driven by burgeoning demand from biotech firms, pharmaceutical companies, and research institutions. As of 2023, the U.S. life science real estate market was valued at around $35 billion, with a compound annual growth rate of approximately 10%. This surge is fueled by increased investment in biomedical research, an aging population requiring more healthcare services, and the continuous evolution of biotechnology.

Key markets for life science real estate include Boston, San Francisco, and San Diego, known for their robust ecosystems of research universities, hospitals, and biotech startups. These areas offer a unique blend of talent, technology, and capital, making them attractive for both developers and tenants. Boston, for example, has over 30 million square feet of lab space, underscoring its position as a leading hub in this sector.

The design and construction of life science facilities are highly specialized, requiring advanced ventilation systems, clean rooms, and adaptable lab spaces. The capital expenditure per square foot for life science buildings is significantly higher than traditional office spaces, often exceeding 50-60%. This reflects the complex infrastructure and stringent regulatory requirements essential for research and development activities.

Investors and developers are increasingly recognizing the resilience and long-term potential of the life science real estate market. Institutional investors, such as pension funds and REITs, are actively expanding their portfolios in this sector. The robust demand for life science facilities, coupled with the limited supply of suitable spaces, has led to low vacancy rates, typically below 5% in top markets, and robust rent growth, further solidifying its attractiveness as an investment class. The convergence of scientific innovation and real estate development in this field is poised to continue shaping the landscape of the U.S. real estate market.

Developers building in Life Science

308 in the database
Westrise Capital
Westrise Capital
Pittsburgh, Pennsylvania
Westrise Capital cover image
Employees2–10
Principals1
Markets1
Last updated: Aug 17, 2026
The Pinkard Group
The Pinkard Group
DC 20006, USA
The Pinkard Group cover image
Employees11–50
Principals4
Markets1
Last updated: Aug 17, 2026
The RMR Group
The RMR Group
Two Newton Place 255 Washington Street Newton. MA 02458
The RMR Group cover image
Employees501–1,000
Principals9
Markets146
Last updated: Aug 17, 2026
Mosaic Development Partners JV
Mosaic Development Partners JV
PA 19121, USA
Mosaic Development Partners JV cover image
Employees11–50
Principals10
Markets2
Last updated: Aug 17, 2026
The Davis Companies
The Davis Companies
Suite 2111 Boston, MA
The Davis Companies cover image
Employees51–200
Principals15
Markets5
Last updated: Aug 17, 2026
The Chiofaro Company
The Chiofaro Company
1 International Place, #4600 Boston MA
The Chiofaro Company cover image
Employees11–50
Principals5
Markets1
Last updated: Aug 17, 2026
View all 308 developers in Life Science

Top markets for Life Science

  • California· 147
  • Massachusetts· 101
  • Texas· 90
  • New York· 77
  • North Carolina· 70
  • District of Columbia· 66
  • Florida· 66
  • Illinois· 59

Typical unlevered yield on cost

5.0 - 7.0%

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